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Citations in this website

For a full overview of scientific studies regarding denture toxicity and denture detoxification, please check out our Free Report which we are happy to send to you via email.

1. “Many studies show that typical hard resin-based dentures may contain substances like formaldehyde, methyl methacrylate, and phthalates.”
“These and other toxins and allergens may release out of the denture and into the mouth.”
“Conventional resin-based dentures may leach formaldehyde, methyl methacrylate, phthalates, biphenyl, hydroquinone and more.”
“Numerous studies indicate the cytotoxicity of substances that leach from dentures.”

· J. H. Jorge, E. T. Giampaolo, A. L. Machado, C. E. Vergani (August 2003). “Cytotoxicity of denture base acrylic resins: a literature review.” Journal of Prosthetic Dentistry 90 (2): 190-3. PMID 12886213
· P. A. Leggat, U. Kedjarune (June 2003). “Toxicity of methyl methacrylate in dentistry.” International Dental Journal, 53 (3): 126–31. doi: 10.1111/j.1875-595X.2003.tb00736.x PMID 12873108
· N. Çelebi, B. Yüzügüllü, Ş. Canay, Ü. Yücel (March 2008). “Effect of polymerization methods on the residual monomer level of acrylic resin denture base polymers.” Materials Research Innovations 19 (3): 201-206.
· H. M. Kopperud, I. S. Kleven, H. Wellendorf (February 2011). “Identification and quantification of leachable substances from polymer-based orthodontic base-plate materials.” European Journal of Orthodontics 33 (1): 26-31. PMID 20624754
· H. Lygre, E. Solheim, N. R. Gjerdet, E. Berg (February 1993). “Leaching of organic additives from dentures in vivo.” Acta Odontologica Scandinavica 51 (1): 45-51. PMID 8451923
· H. Lygre, E. Solheim, N. R. Gjerdet (April 1995). “Leaching from denture base materials in vitro.” Acta Odontologica Scandinavica 53 (2): 75-80. PMID 7610779
· M. Mikai, M. Koike, H. Fujii (March 2006). “Quantitative analysis of allergenic ingredients in eluate extracted from used denture base resin.” Journal of Oral Rehabilitation 33 (3): 216-20. PMID 16512888
· T. Koda, H. Tsuchiya, M. Yamauchi, Y. Hoshino, N. Takagi, J. Kawano (April 1989). “High-performance liquid chromatographic estimation of eluates from denture base polymers.” Journal of Dentistry 17 (2): 84-9. PMID 2732369
· H. Tsuchiya, Y. Hoshino, H. Kato, N. Takagi (August 1993). “Flow injection analysis of formaldehyde leached from denture-base acrylic resins.” Journal of Dentistry 21 (4): 240-3. PMID 8354750
· A. F. Boeckler, D. Morton, S. Poser, K. E. Dette (December 2008). “Release of dibenzoyl peroxide from polymethyl methacrylate denture base resins: an in vitro evaluation.” Dental Materials 24 (12): 1602-7. PMID 18471871
· C. A. Chaves, A. L. Machado, I. Z. Carlos, E. T. Giampaolo, A. C. Pavarina, C. E. Vergani (October 2010). “Cytotoxicity of monomers, plasticizer and degradation by-products released from dental hard chairside reline resins.” Dental Materials 26 (10): 1017-23. PMID 20650509
· F. Purello-D'Ambrosio, S. Gangemi, P. Minciullo, L. Ricciardi, R. A. Merendino (March-April 2000). “Burning mouth syndrome due to cadmium in a denture wearer.” Journal of Investigational Allergology and Clinical Immunology 10 (2): 105-6. PMID 10880000
· N. Pradeep, A. V. Sreekumar (November 2012). “An in vitro investigation into the cytotoxicity of methyl methacrylate monomer.” Journal of Contemporary Dental Practice 13 (6): 838-41. PMID 23404013
· A. Sofou, I. Tsoupi, J. Emmanouil, M. Karayannis (2005). “HPLC determination of residual monomers released from heat-cured acrylic resins.” Analytical and Bioanalytical Chemistry 381 (7): 1336-46. PMID 15759139

2. “Reported health effects include irritation, sensitization, inflammation, denture stomatitis, burning mouth syndrome and allergic reactions.”
“Leached substances can also cause irritation or sensitization.”

· J. H. Jorge, E. T. Giampaolo, A. L. Machado, C. E. Vergani (August 2003). “Cytotoxicity of denture base acrylic resins: a literature review.” Journal of Prosthetic Dentistry 90 (2): 190-3. PMID 12886213
· P. A. Leggat, U. Kedjarune (June 2003). “Toxicity of methyl methacrylate in dentistry.” International Dental Journal, 53 (3): 126–31. doi: 10.1111/j.1875-595X.2003.tb00736.x PMID 12873108
· C. Bural, E. Aktaş, G. Deniz, Y. Ünlüçerçi, G. Bayraktar (August 2011). “Effect of leaching residual methyl methacrylate concentrations on in vitro cytotoxicity of heat polymerized denture base acrylic resin processed with different polymerization cycles.” Journal of Applied Oral Science 19 (4): 306-12. PMID 21956586 · P. Pfeiffer, E. U. Rosenbauer (July 2004). “Residual methyl methacrylate monomer, water sorption, and water solubility of hypoallergenic denture base materials.” Journal of Prosthetic Dentistry 92 (1): 72-78. PMID 15232564
· H. Tsuchiya, Y. Hoshino, K. Tajima, N. Takagi (June 1994). “Leaching and cytotoxicity of formaldehyde and methyl methacrylate from acrylic resin denture base materials.” The Journal of Prosthetic Dentistry 71 (6): 618-24. PMID 8040827
· M. Mikai, M. Koike, H. Fujii (March 2006). “Quantitative analysis of allergenic ingredients in eluate extracted from used denture base resin.” Journal of Oral Rehabilitation 33 (3): 216-20. PMID 16512888
· D. Koutis, S. Freeman (August 2001). “Allergic contact stomatitis caused by acrylic monomer in a denture.” Australasian Journal of Dermatology 42 (3): 202-6. PMID 11488717
· T. S. Gonçalves, M. A. Morganti, L. C. Campos, S. M. D. Rizzatto, L. M. Menezes (March 2006). “Allergy to auto-polymerized acrylic resin in an orthodontic patient.” American Journal of Orthodontics & Dentofacial Orthopedics 29 (3): 431-5. PMID 16527642
· A. J. Feilzer (September 2009). “Burning mouth caused by denture material.” Nederlands Tijdschrirft voor Tandheelkunde 116 (9): 472d-4. PMID 19791489
· M. R. Cimpan, L. I. Cressey, N. Skaug, A. Halstensen, S. A. Lie, B. T. Gjertsen, R. Matre (February 2000). “Patterns of cell death induced by eluates from denture base acrylic resins in U-937 human monoblastoid cells.” European Journal of Oral Sciences 108 (1): 59-69. PMID 10706479

3. “Dentures that leach methyl methacrylate and formaldehyde synergistically promote microbial proliferation, a cause of denture stomatitis.”

· N. Aníl and M. T. Ercan (October 2000). “Microleakage Study Of Various Soft Denture Liners By Autoradiography: Effect Of Accelerated Aging.” Journal of Prosthetic Dentistry 81: 394-399. PMID 11044844

4. “MRSA, a drug-resistant staphylococcus aureus bacteria, is a biofilm that can grow on dentures. When breathed into the lungs it can cause pneumonia.”

· K. T. Altieri, P. V. Sanitá, A. L. Machado, E. T. Giampaolo, A. C. Pavarina, J. H. Jorge, C. E. Vergani (September 2013). “Eradication of a Mature Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilm From Acrylic Surfaces.” Brazilian Dental (24) 5.
· K. Okuda, R. Kimizuka, S. Abe, T. Kato, K. Ishihara (November 2005). “Involvement of Periodontopathic Anaerobes in Aspiration Pneumonia.” Journal of Periodontology 76 (11-s): 2154-2160.

5. “If a denture can leach substances out, it can also absorb substances into it.”

· P. Pfeiffer, E. U. Rosenbauer (July 2004). “Residual methyl methacrylate monomer, water sorption, and water solubility of hypoallergenic denture base materials.” Journal of Prosthetic Dentistry 92 (1): 72-78. PMID 15232564
· Golbidi, F., G. Asghari. “The Level of Residual Monomer in Acrylic Denture Base Materials.” Research Journal of Biological Sciences 4 (2): 244-249. 2009.

For a full overview of scientific studies regarding denture toxicity and denture detoxification, please check out our Free Report which we are happy to send to you via email.